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1LQE

CRYSTAL STRUCTURE OF TRYPSIN IN COMPLEX WITH 79.

Summary for 1LQE
Entry DOI10.2210/pdb1lqe/pdb
Related1LPG 1LPK 1LPZ 1LQD
DescriptorTRYPSIN, CALCIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywordsfactor xa inhibitor, enzyme-inhibitor complex, blood coagulation factor, serine proteinase, hydrolase
Biological sourceBos taurus (cattle)
Cellular locationSecreted, extracellular space: P00760
Total number of polymer chains1
Total formula weight26127.54
Authors
Schreuder, H.A.,Liesum, A. (deposition date: 2002-05-10, release date: 2003-05-10, Last modification date: 2011-07-13)
Primary citationMatter, H.,Defossa, E.,Heinelt, U.,Blohm, P.M.,Schneider, D.,Mueller, A.,Herok, S.,Schreuder, H.A.,Liesum, A.,Brachvogel, V.,Loenze, P.,Walser, A.,Al-Obeidi, F.,Wildgoose, P.
Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.
J.Med.Chem., 45:2749-2769, 2002
Cited by
PubMed: 12061878
DOI: 10.1021/jm0111346
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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