1LKI

THE CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTION OF LEUKEMIA INHIBITORY FACTOR: IMPLICATIONS FOR RECEPTOR BINDING

Summary for 1LKI

DescriptorLEUKEMIA INHIBITORY FACTOR (2 entities in total)
Functional Keywordscytokine, four helix bundle
Biological sourceMus musculus (house mouse)
Cellular locationSecreted P09056
Total number of polymer chains1
Total molecular weight19891.01
Authors
Robinson, R.C.,Grey, L.M.,Staunton, D.,Stuart, D.I.,Heath, J.K.,Jones, E.Y. (deposition date: 1994-12-12, release date: 1995-03-31, Last modification date: 2011-07-13)
Primary citation
Robinson, R.C.,Grey, L.M.,Staunton, D.,Vankelecom, H.,Vernallis, A.B.,Moreau, J.F.,Stuart, D.I.,Heath, J.K.,Jones, E.Y.
The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding.
Cell(Cambridge,Mass.), 77:1101-1116, 1994
PubMed: 8020098 (PDB entries with the same primary citation)
DOI: 10.1016/0092-8674(94)90449-9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers4012.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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