1KXR
Crystal Structure of Calcium-Bound Protease Core of Calpain I
Summary for 1KXR
Entry DOI | 10.2210/pdb1kxr/pdb |
Related | 1AJ5 1ALW 1DF0 1DVI 1KFU 1KFX |
Descriptor | thiol protease DOMAINS I AND II, CALCIUM ION (3 entities in total) |
Functional Keywords | papain-related, calcium-dependent cysteine protease, two novel cooperative calcium sites, hydrolase |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cytoplasm (By similarity): P97571 |
Total number of polymer chains | 2 |
Total formula weight | 77737.29 |
Authors | Moldoveanu, T.,Hosfield, C.M.,Lim, D.,Elce, J.S.,Jia, Z.,Davies, P.L. (deposition date: 2002-02-01, release date: 2002-03-20, Last modification date: 2023-08-16) |
Primary citation | Moldoveanu, T.,Hosfield, C.M.,Lim, D.,Elce, J.S.,Jia, Z.,Davies, P.L. A Ca(2+) switch aligns the active site of calpain. Cell(Cambridge,Mass.), 108:649-660, 2002 Cited by PubMed: 11893336DOI: 10.1016/S0092-8674(02)00659-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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