1KBO
Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340)
Summary for 1KBO
Entry DOI | 10.2210/pdb1kbo/pdb |
Related | 1D4A 1GG5 1H66 1H69 1KBQ 1QRD |
Descriptor | NAD(P)H dehydrogenase [quinone] 1, 5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | flavoenzyme, prodrug-enzyme complex, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P15559 |
Total number of polymer chains | 4 |
Total formula weight | 127493.18 |
Authors | Faig, M.,Bianchet, M.A.,Amzel, L.M. (deposition date: 2001-11-06, release date: 2002-01-16, Last modification date: 2024-02-07) |
Primary citation | Winski, S.L.,Faig, M.,Bianchet, M.A.,Siegel, D.,Swann, E.,Fung, K.,Duncan, M.W.,Moody, C.J.,Amzel, L.M.,Ross, D. Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches. Biochemistry, 40:15135-15142, 2001 Cited by PubMed: 11735396DOI: 10.1021/bi011324i PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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