1KBC

PROCARBOXYPEPTIDASE TERNARY COMPLEX

Summary for 1KBC

• Entry DOI: 10.2210/pdb1kbc/pdb
• Descriptor: NEUTROPHIL COLLAGENASE, CALCIUM ION, ZINC ION, ... (6 entities in total)
• Functional Keywords: hydrolytic enzyme, metalloproteinase, collagenase, matrixin, mmp-8, hnc, inhibitor, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasmic granule: P22894
• Total number of polymer chains: 2
• Total formula weight: 37742.87

Authors

Betz, M.,Gomis-Rueth, F.X.,Bode, W. (deposition date: 1997-04-29, release date: 1997-08-12, Last modification date: 2024-02-07)

• Primary citation: Betz, M.,Huxley, P.,Davies, S.J.,Mushtaq, Y.,Pieper, M.,Tschesche, H.,Bode, W.,Gomis-Ruth, F.X.; 1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile.; Eur.J.Biochem., 247:356-363, 1997; PubMed: 9249047; DOI: 10.1111/j.1432-1033.1997.00356.x

Experimental method

X-RAY DIFFRACTION (1.8 Å)