1JU5
Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy
Summary for 1JU5
Entry DOI | 10.2210/pdb1ju5/pdb |
Related | 1AWO 1AYA 1BBZ 1SPS 2ABL 2PLD |
Descriptor | Crk, Abl (3 entities in total) |
Functional Keywords | crk, sh2, abl, sh3, adaptor protein, phosphopeptide, protein binding-transferase complex, protein binding/transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): P46108 Q64010 Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 3 |
Total formula weight | 20375.51 |
Authors | Donaldson, L.W.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D. (deposition date: 2001-08-23, release date: 2002-11-06, Last modification date: 2021-11-10) |
Primary citation | Donaldson, L.W.,Gish, G.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D. Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide Proc.Natl.Acad.Sci.USA, 99:14053-14058, 2002 Cited by PubMed: 12384576DOI: 10.1073/pnas.212518799 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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