1IHT

CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6

Summary for 1IHT
DescriptorALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUTONIN-6, ... (4 entities in total)
Functional Keywordsserine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P28504
Secreted: P00734
Total number of polymer chains3
Total formula weight35412.56
Authors
Zdanov, A.,Cygler, M. (deposition date: 1993-08-04, release date: 1994-01-31, Last modification date: 2011-07-13)
Primary citationCygler, M.,DiMaio, J.,Edwards, B.F.,Konishi, Y.,Li, Y.,Martin, P.D.,Wu, S.,Wu, X.,Zdanov, A.
Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.
Proteins, 17:252-265, 1993
PubMed: 8272424
DOI: 110.1002/prot.340170304
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation
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PDB entries from 2021-06-23