1IHT
CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | ALPHA-THROMBIN (SMALL SUBUNIT) | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
| 2 | H | ALPHA-THROMBIN (LARGE SUBUNIT) | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 3 | I | HIRUTONIN-6 | polymer | 13 | 1535.8 | 1 | UniProt (P28504) UniProt (by SIFTS) (P09944) In PDB | ||
| 4 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
I: 55 - 61 (UniProt: P28504)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | insertion |
| Dpn 1 | - | insertion |
| Pro 2 | - | insertion |
| A5r 3 | - | insertion |
| Fbe 4 | - | insertion |
| Fbe 5 | - | insertion |
| Pro 58 | Glu 58 | conflict |
| Leu 61 | Glu 61 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35412.6 | |
| All* | Total formula weight | 35412.6 |
