1I7G
CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN FROM HUMAN PPAR-ALPHA IN COMPLEX WITH THE AGONIST AZ 242
Summary for 1I7G
Entry DOI | 10.2210/pdb1i7g/pdb |
Related | 1I7I |
Descriptor | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA, SODIUM ION, (2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACID, ... (5 entities in total) |
Functional Keywords | anti parallel helix sandwich, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q07869 |
Total number of polymer chains | 1 |
Total formula weight | 33630.86 |
Authors | Petersen, J.F.W.,Cronet, P.,Folmer, R.,Blomberg, N.,Sjoblom, K.,Karlsson, U.,Lindstedt, E.-L.,Bamberg, K. (deposition date: 2001-03-09, release date: 2002-03-09, Last modification date: 2023-08-09) |
Primary citation | Cronet, P.,Petersen, J.F.,Folmer, R.,Blomberg, N.,Sjoblom, K.,Karlsson, U.,Lindstedt, E.L.,Bamberg, K. Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family. Structure, 9:699-706, 2001 Cited by PubMed: 11587644DOI: 10.1016/S0969-2126(01)00634-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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