1I7G
CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN FROM HUMAN PPAR-ALPHA IN COMPLEX WITH THE AGONIST AZ 242
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA | polymer | 287 | 32337.3 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens (human) | PPAR-ALPHA |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 3 | C (A) | (2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACID | non-polymer | 408.5 | 1 | Chemie (AZ2) PubChem (208901) PubChem (11338777) PubChem (57823090) | |||
| 4 | D (A) | N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | non-polymer | 862.1 | 1 | Chemie (CPQ) PubChem (124905379) PubChem (124919195) PubChem (124933354) PubChem (446320) PubChem (102565423) PubChem (3609263) PubChem (122130317) PubChem (124837856) PubChem (124867695) PubChem (124905378) PubChem (124905380) PubChem (124905381) PubChem (124919192) PubChem (124919193) PubChem (124919194) PubChem (124933353) PubChem (124933355) PubChem (124933356) PubChem (125027417) PubChem (129891641) PubChem (132470929) PubChem (135639079) PubChem (16402218) PubChem (139981181) PubChem (44658112) PubChem (46936249) PubChem (171036883) PubChem (71299811) PubChem (75361254) PubChem (90277687) PubChem (45933557) | |||
| 5 | E (A) | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A: 196 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 182 | - | cloning artifact |
| Ser 183 | - | cloning artifact |
| His 184 | - | cloning artifact |
| Met 185 | - | cloning artifact |
| Ser 186 | - | cloning artifact |
| Gly 187 | - | cloning artifact |
| Glu 188 | - | cloning artifact |
| Asp 189 | - | cloning artifact |
| Ser 190 | - | cloning artifact |
| Glu 191 | - | cloning artifact |
| Thr 192 | - | cloning artifact |
| Glu 193 | - | cloning artifact |
| Ala 194 | - | cloning artifact |
| Asp 195 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32337.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1293.5 | |
| All* | Total formula weight | 33630.9 |
