1HQ2

CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION

Summary for 1HQ2

Entry DOI	10.2210/pdb1hq2/pdb
Related	1CBK 1DY3 1EQ0 1EQM 1EQO 1EX8 1F9H 1F9Y 1G4C 1HKA
Descriptor	6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	pyrophosphokinase, pyrophosphoryl transfer, catalytic mechanism, folate, hppk, pterin, 6-hydroxymethyl-7, 8-dihydropterin, ternary complex, substrate specificity, antimicrobial agent, drug design, transferase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	18901.04
Authors	Blaszczyk, J.,Ji, X. (deposition date: 2000-12-13, release date: 2003-04-15, Last modification date: 2023-08-30)
Primary citation	Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X. Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry, 42:1573-1580, 2003 Cited by PubMed: 12578370 DOI: 10.1021/bi0267994 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation