1HQ2
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE | polymer | 158 | 17880.4 | 1 | UniProt (P26281) Pfam (PF01288) | Escherichia coli | 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE, HPPK |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E, F, G, H (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | I (A) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 1 | Chemie (APC) | |||
| 6 | J (A) | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE | non-polymer | 195.2 | 1 | Chemie (PH2) | |||
| 7 | K (A) | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A: 1 - 158 (UniProt: P26281)
| PDB | External Database | Details |
|---|---|---|
| Ala 82 | Arg 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17880.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1020.6 | |
| All* | Total formula weight | 18901.0 |
