1H2G
Altered substrate specificity mutant of penicillin acylase
Summary for 1H2G
| Entry DOI | 10.2210/pdb1h2g/pdb |
| Related | 1AI4 1AI5 1AI6 1AI7 1AJN 1AJP 1AJQ 1CP9 1E3A 1FXH 1FXV 1GK9 1GKF 1GM7 1GM8 1GM9 1PNK 1PNL 1PNM |
| Descriptor | PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ... (5 entities in total) |
| Functional Keywords | amidohydrolase, antibiotic resistance, altered specificity, zymogen, hydrolase |
| Biological source | ESCHERICHIA COLI More |
| Cellular location | Periplasm: P06875 P06875 |
| Total number of polymer chains | 2 |
| Total formula weight | 86522.65 |
| Authors | McVey, C.E.,Morillas, M.,Brannigan, J.A.,Ladurner, A.G.,Forney, L.J.,Virden, R. (deposition date: 2002-08-08, release date: 2003-07-17, Last modification date: 2023-12-13) |
| Primary citation | Morillas, M.,Mcvey, C.E.,Brannigan, J.A.,Ladurner, A.G.,Forney, L.J.,Virden, R. Mutations of Penicillin Acylase Residue B71 Extend Substrate Specificity by Decreasing Steric Constraints for Substrate Binding Biochem.J., 371:143-, 2003 Cited by PubMed: 12511194DOI: 10.1042/BJ20021383 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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