1E3A

A slow processing precursor penicillin acylase from Escherichia coli

Summary for 1E3A

Related1PNK 1PNL 1PNM 1AI4 1AI5 1AI6 1AI7 1AJN 1AJP 1AJQ
DescriptorPENICILLIN AMIDASE ALPHA SUBUNIT, PENICILLIN AMIDASE BETA SUBUNIT, CALCIUM ION, ... (6 entities in total)
Functional Keywordsantibiotic resistance, amidase, ntn-hydrolase, hydrolysis of penicillin g acylase
Biological sourceESCHERICHIA COLI
Cellular locationPeriplasm P06875 P06875
Total number of polymer chains2
Total molecular weight91910.2
Authors
Hewitt, L.,Kasche, V.,Lummer, K.,Lewis, R.J.,Murshudov, G.N.,Verma, C.S.,Dodson, G.G.,Wilson, K.S. (deposition date: 2000-06-07, release date: 2000-11-29, Last modification date: 2014-10-22)
Primary citation
Hewitt, L.,Kasche, V.,Lummer, K.,Lewis, R.J.,Murshudov, G.N.,Verma, C.S.,Dodson, G.G.,Wilson, K.S.
Structure of a Slow Processing Precursor Penicillin Acylase from Escherichia Coli Reveals the Linker Peptide Blocking the Active-Site Cleft
J.Mol.Biol., 302:887-, 2000
PubMed: 10993730 (PDB entries with the same primary citation)
DOI: 10.1006/JMBI.2000.4105
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers60.1%2.4%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1e3a
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Molmil generated image of 1e3a
rotated about x axis by 90°
Molmil generated image of 1e3a
rotated about y axis by 90°