1H15
X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase
Summary for 1H15
Entry DOI | 10.2210/pdb1h15/pdb |
Related | 1A6A 1AQD 1D5M 1D5X 1D5Z 1D6E 1DLH 1FV1 1HQR 1HXY 1J8H 1KG0 1SEB 2SEB |
Descriptor | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAIN, DNA POLYMERASE, ... (6 entities in total) |
Functional Keywords | immune system/transferase, complex (mhc-antigen), immune system, mhc, hla, class ii, dr2, drb5, ebv, dna polymerase, dna-directed dna polymerase, immune system-transferase complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 Host nucleus: P03198 |
Total number of polymer chains | 6 |
Total formula weight | 91120.68 |
Authors | Lang, H.,Jacobsen, H.,Ikemizu, S.,Andersson, C.,Harlos, K.,Madsen, L.,Hjorth, P.,Sondergaard, L.,Svejgaard, A.,Wucherpfennig, K.,Stuart, D.I.,Bell, J.I.,Jones, E.Y.,Fugger, L. (deposition date: 2002-07-02, release date: 2002-10-03, Last modification date: 2023-12-13) |
Primary citation | Lang, H.,Jacobsen, H.,Ikemizu, S.,Andersson, C.,Harlos, K.,Madsen, L.,Hjorth, P.,Sondergaard, L.,Svejgaard, A.,Wucherpfennig, K.,Stuart, D.I.,Bell, J.I.,Jones, E.Y.,Fugger, L. A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis Nat.Immunol., 3:940-, 2002 Cited by PubMed: 12244309DOI: 10.1038/NI835 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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