1G4U
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1
Summary for 1G4U
Entry DOI | 10.2210/pdb1g4u/pdb |
Related | 1G4W |
NMR Information | BMRB: 5511 |
Descriptor | PROTEIN TYROSINE PHOSPHATASE SPTP, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | virulence factor, gap, tyrosine phosphatase, 4-helix bundle, gtpase, signaling protein |
Biological source | Salmonella typhimurium More |
Cellular location | Secreted : P74873 Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000 |
Total number of polymer chains | 2 |
Total formula weight | 63081.93 |
Authors | Stebbins, C.E.,Galan, J.E. (deposition date: 2000-10-28, release date: 2001-01-24, Last modification date: 2024-02-07) |
Primary citation | Stebbins, C.E.,Galan, J.E. Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1. Mol.Cell, 6:1449-1460, 2000 Cited by PubMed: 11163217DOI: 10.1016/S1097-2765(00)00141-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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