1G30
THROMBIN INHIBITOR COMPLEX
Summary for 1G30
Entry DOI | 10.2210/pdb1g30/pdb |
Descriptor | PROTHROMBIN, HIRUDIN IIB, [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER, ... (5 entities in total) |
Functional Keywords | blood coagulation, factor xa, inhibitor complexes, serine proteinase, blood coagulation cascade, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 35893.88 |
Authors | |
Primary citation | Nar, H.,Bauer, M.,Schmid, A.,Stassen, J.M.,Wienen, W.,Priepke, H.W.,Kauffmann, I.K.,Ries, U.J.,Hauel, N.H. Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors. Structure, 9:29-38, 2001 Cited by PubMed: 11342132DOI: 10.1016/S0969-2126(00)00551-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report