1FRB
FR-1 PROTEIN/NADPH/ZOPOLRESTAT COMPLEX
Summary for 1FRB
| Entry DOI | 10.2210/pdb1frb/pdb |
| Descriptor | FR-1 PROTEIN, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, ... (4 entities in total) |
| Functional Keywords | aldo-keto oxidoreductase (nadp), tim barrel, oxidoreductase (nadp) |
| Biological source | Mus musculus (house mouse) |
| Cellular location | Cytoplasm (By similarity): P45377 |
| Total number of polymer chains | 1 |
| Total formula weight | 37201.05 |
| Authors | Wilson, D.K.,Quiocho, F.A. (deposition date: 1995-08-08, release date: 1996-10-14, Last modification date: 2024-02-07) |
| Primary citation | Wilson, D.K.,Nakano, T.,Petrash, J.M.,Quiocho, F.A. 1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor. Biochemistry, 34:14323-14330, 1995 Cited by PubMed: 7578036DOI: 10.1021/bi00044a009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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