1FM1

SOLUTION STRUCTURE OF THE CATALYTIC FRAGMENT OF HUMAN COLLAGENASE-3 (MMP-13) COMPLEXED WITH A HYDROXAMIC ACID INHIBITOR

Summary for 1FM1

• Entry DOI: 10.2210/pdb1fm1/pdb
• Related: 1FLS
• NMR Information: BMRB: 4679
• Descriptor: COLLAGENASE-3, ZINC ION, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: matrix metalloproteinase, hydroxamic acid, human collagenase-3, mmp-13, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix (Probable): P45452
• Total number of polymer chains: 1
• Total formula weight: 19206.19

Authors

Moy, F.J.,Chanda, P.K.,Chen, J.M.,Cosmi, S.,Edris, W.,Levin, J.I.,Powers, R. (deposition date: 2000-08-15, release date: 2001-08-15, Last modification date: 2022-02-23)

• Primary citation: Moy, F.J.,Chanda, P.K.,Chen, J.M.,Cosmi, S.,Edris, W.,Levin, J.I.,Powers, R.; High-resolution solution structure of the catalytic fragment of human collagenase-3 (MMP-13) complexed with a hydroxamic acid inhibitor.; J.Mol.Biol., 302:671-689, 2000; PubMed: 10986126; DOI: 10.1006/jmbi.2000.4082

Experimental method

SOLUTION NMR