1FD0
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254
Summary for 1FD0
Entry DOI | 10.2210/pdb1fd0/pdb |
Related | 1EXA 1EXX 1fcx 1fcy 1fcz 2LBD 3LBD |
Descriptor | RETINOIC ACID RECEPTOR GAMMA-1, 6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total) |
Functional Keywords | isotype selectivity, retinoid ligand complexes, drug design, antiparallel alpha-helical sandwich fold, ch...o hydrogen bond, structural proteomics in europe, spine, structural genomics, gene regulation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 27447.18 |
Authors | Klaholz, B.P.,Moras, D.,Structural Proteomics in Europe (SPINE) (deposition date: 2000-07-19, release date: 2002-09-27, Last modification date: 2023-08-09) |
Primary citation | Klaholz, B.,Moras, D. C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity. Structure, 10:1197-1204, 2002 Cited by PubMed: 12220491DOI: 10.1016/S0969-2126(02)00828-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.38 Å) |
Structure validation
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