1F73

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM III IN COMPLEX WITH SIALIC ACID ALDITOL

Summary for 1F73

Related1NAL 1FDY 1FDZ 1F5Z 1F6K 1F6P 1F73 1F7B 1F74
DescriptorN-ACETYL NEURAMINATE LYASE, 2,4,6,7,8,9-HEXAHYDROXY-5-METHYLCARBOXAMIDO NONANOIC ACID, GLYCEROL, ... (4 entities in total)
Functional Keywordsbeta barrel, lyase
Biological sourceHaemophilus influenzae
Cellular locationCytoplasm P44539
Total number of polymer chains4
Total molecular weight131583.52
Authors
Barbosa, J.A.R.G.,Smith, B.J.,DeGori, R.,Lawrence, M.C. (deposition date: 2000-06-25, release date: 2000-11-22, Last modification date: 2011-07-13)
Primary citation
Barbosa, J.A.R.G.,Smith, B.J.,DeGori, R.,Ooi, H.C.,Marcuccio, S.M.,Campi, E.M.,Jackson, W.R.,Brossmer, R.,Sommer, M.,Lawrence, M.C.
Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303:405-421, 2000
PubMed: 11031117 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2000.4138
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2335 0.4% 2.8% 2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25