1F7B

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID

Summary for 1F7B

Entry DOI	10.2210/pdb1f7b/pdb
Related	1F5Z 1F6K 1F73 1FDY 1FDZ 1NAL
Descriptor	N-ACETYL-NEURAMINATE LYASE, 4,4,6,7,8,9-HEXAHYDROXY-5-METHYLCARBOXAMIDONONANOIC ACID, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	beta barrel, lyase
Biological source	Haemophilus influenzae
Cellular location	Cytoplasm: P44539
Total number of polymer chains	2
Total formula weight	65763.15
Authors	Barbosa, J.A.R.G.,Smith, B.J.,DeGori, R.,Lawrence, M.C. (deposition date: 2000-06-26, release date: 2000-11-22, Last modification date: 2011-07-13)
Primary citation	Barbosa, J.A.R.G.,Smith, B.J.,DeGori, R.,Ooi, H.C.,Marcuccio, S.M.,Campi, E.M.,Jackson, W.R.,Brossmer, R.,Sommer, M.,Lawrence, M.C. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J.Mol.Biol., 303:405-421, 2000 Cited by PubMed: 11031117 DOI: 10.1006/jmbi.2000.4138 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation