Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008747 | molecular_function | N-acetylneuraminate lyase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0008747 | molecular_function | N-acetylneuraminate lyase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019262 | biological_process | N-acetylneuraminate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 900 |
| Chain | Residue |
| C | TYR180 |
| C | PRO181 |
| C | ASN182 |
| C | HIS183 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAU A 901 |
| Chain | Residue |
| A | TYR136 |
| A | LYS164 |
| A | GLY188 |
| A | PHE189 |
| A | ASP190 |
| A | GLU191 |
| A | ILE205 |
| A | GLY206 |
| A | SER207 |
| A | LEU250 |
| A | HOH1214 |
| A | HOH1215 |
| A | HOH1297 |
| A | ALA10 |
| A | TYR43 |
| A | GLY46 |
| A | SER47 |
| A | THR48 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NAV C 902 |
| Chain | Residue |
| C | ALA10 |
| C | TYR43 |
| C | GLY46 |
| C | SER47 |
| C | THR48 |
| C | TYR136 |
| C | LYS164 |
| C | GLY188 |
| C | PHE189 |
| C | ASP190 |
| C | GLU191 |
| C | ILE205 |
| C | GLY206 |
| C | SER207 |
| C | LEU250 |
| C | HOH1185 |
Functional Information from PROSITE/UniProt
| site_id | PS00217 |
| Number of Residues | 26 |
| Details | SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. VdGLYvGGstgenfmLstEekkeifR |
| Chain | Residue | Details |
| A | VAL39-ARG64 | |
| site_id | PS00228 |
| Number of Residues | 4 |
| Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MRDL |
| Chain | Residue | Details |
| A | MET1-LEU4 | |
| site_id | PS00665 |
| Number of Residues | 18 |
| Details | DHDPS_1 Dihydrodipicolinate synthase signature 1. GLYvgGSTGENfmlsteE |
| Chain | Residue | Details |
| A | GLY41-GLU58 | |
| site_id | PS00666 |
| Number of Residues | 31 |
| Details | DHDPS_2 Dihydrodipicolinate synthase signature 2. YSIPflTgvnMgieqfgelyknpk.VlGVKFT |
| Chain | Residue | Details |
| A | TYR136-THR166 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01237","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11031117","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate","evidences":[{"source":"HAMAP-Rule","id":"MF_01237","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11031117","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01237","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| A | TYR136 | |
| A | LYS164 | |
| A | LEU141 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| A | THR48 | |
| A | LYS164 | |
| A | SER47 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhp |
| Chain | Residue | Details |
| C | THR48 | |
| C | LYS164 | |
| C | SER47 | |
