1E4H

Structure of human transthyretin complexed with bromophenols: a new mode of binding

Summary for 1E4H

Related1TTA 2PAB 1THC 1THA 1TLM 1TTB 1TTC 1ETA 1ETB 1RLB 1TYR 1BM7 1BMZ 1QAB 2TRH 2TRY 2ROX 2ROY 1TTR 1TSH 1E3F 1BZD 1BZE 1BZ8 5TTR 1E5A
DescriptorTRANSTHYRETIN, GLYCEROL, PENTABROMOPHENOL, ... (4 entities in total)
Functional Keywordstransport protein, transport(thyroxine), environmental pollutants, bromophenols
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P02766
Total number of polymer chains2
Total molecular weight28716.09
Authors
Ghosh, M.,Meerts, I.A.T.M.,Cook, A.,Bergman, A.,Brouwer, A.,Johnson, L.N. (deposition date: 2000-07-04, release date: 2000-08-29, Last modification date: 2017-07-05)
Primary citation
Ghosh, M.,Meerts, I.A.T.M.,Cook, A.,Bergman, A.,Brouwer, A.,Johnson, L.N.
Structure of Human Transthyretin Complexed with Bromophenols : A New Mode of Binding
Acta Crystallogr.,Sect.D, 56:1085-, 2000
PubMed: 10957627 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444900008568
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers701.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload