1DVA
Crystal Structure of the Complex Between the Peptide Exosite Inhibitor E-76 and Coagulation Factor VIIA
Summary for 1DVA
Entry DOI | 10.2210/pdb1dva/pdb |
Related | 1CVW 1DAN 1FAK 1QFK |
Related PRD ID | PRD_000369 PRD_900004 |
Descriptor | DES-GLA FACTOR VIIA (HEAVY CHAIN), beta-L-fucopyranose, DES-GLA FACTOR VIIA (LIGHT CHAIN), ... (11 entities in total) |
Functional Keywords | protein-peptide complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 85049.09 |
Authors | Eigenbrot, C.,Ultsch, M.H. (deposition date: 2000-01-20, release date: 2000-05-12, Last modification date: 2020-07-29) |
Primary citation | Dennis, M.S.,Eigenbrot, C.,Skelton, N.J.,Ultsch, M.H.,Santell, L.,Dwyer, M.A.,O'Connell, M.P.,Lazarus, R.A. Peptide exosite inhibitors of factor VIIa as anticoagulants. Nature, 404:465-470, 2000 Cited by PubMed: 10761907DOI: 10.1038/35006574 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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