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1DVA

Crystal Structure of the Complex Between the Peptide Exosite Inhibitor E-76 and Coagulation Factor VIIA

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
H0004252molecular_functionserine-type endopeptidase activity
H0006508biological_processproteolysis
I0004252molecular_functionserine-type endopeptidase activity
I0006508biological_processproteolysis
L0005509molecular_functioncalcium ion binding
M0005509molecular_functioncalcium ion binding
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00010
残基数12
詳細ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDqlqsYiCfC
鎖名残基詳細
LCYS61-CYS72

site_idPS00022
残基数12
詳細EGF_1 EGF-like domain signature 1. CfClpAfeGRnC
鎖名残基詳細
LCYS70-CYS81

site_idPS00134
残基数6
詳細TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC
鎖名残基詳細
HVAL53-CYS58

site_idPS00135
残基数12
詳細TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA
鎖名残基詳細
HASP189-ALA200

site_idPS01186
残基数16
詳細EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC
鎖名残基詳細
LCYS112-CYS127

site_idPS01187
残基数25
詳細EGF_CA Calcium-binding EGF-like domain signature. DgDQCassp..........Cqnggs..CkDqlqsYiC
鎖名残基詳細
LASP46-CYS70

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数2
詳細SITE: Important for S-112 for O-xylosylation
鎖名残基詳細
LSER53
MSER53
HSER195
IHIS57
IASP102
ISER195

site_idSWS_FT_FI2
残基数2
詳細MOD_RES: (3R)-3-hydroxyaspartate => ECO:0000269|PubMed:3264725
鎖名残基詳細
LASP63
MASP63

site_idSWS_FT_FI3
残基数2
詳細CARBOHYD: O-linked (Xyl...) serine; alternate => ECO:0000269|PubMed:1904059, ECO:0000269|PubMed:2129367, ECO:0000269|PubMed:21949356, ECO:0000269|PubMed:2511201
鎖名残基詳細
LSER52
MSER52

site_idSWS_FT_FI4
残基数2
詳細CARBOHYD: O-linked (Fuc) serine => ECO:0000269|PubMed:1904059, ECO:0000269|PubMed:9023546
鎖名残基詳細
LSER60
MSER60

CSAにおける酵素触媒機能の情報
site_idCSA1
残基数3
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
HASP102
HSER195
HHIS57

site_idCSA2
残基数3
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
IASP102
ISER195
IHIS57

site_idCSA3
残基数4
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
HASP102
HSER195
HGLY193
HHIS57

site_idCSA4
残基数4
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
IASP102
ISER195
IGLY193
IHIS57

site_idCSA5
残基数4
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
HASP102
HSER195
HHIS57
HGLY196

site_idCSA6
残基数4
詳細Annotated By Reference To The Literature 1a0j
鎖名残基詳細
IASP102
ISER195
IHIS57
IGLY196

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件を2025-04-02に公開中

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