1DVA
Crystal Structure of the Complex Between the Peptide Exosite Inhibitor E-76 and Coagulation Factor VIIA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (H, I) | DES-GLA FACTOR VIIA (HEAVY CHAIN) | polymer | 254 | 28103.3 | 2 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | B, E (L, M) | DES-GLA FACTOR VIIA (LIGHT CHAIN) | polymer | 101 | 10994.2 | 2 | UniProt (P08709) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | |
| 3 | C, F (X, Y) | PEPTIDE E-76 | polymer | 20 | 2198.5 | 2 | |||
| 4 | G (A) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 5 | H, N (H, I) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide | non-polymer | 504.0 | 2 | BIRD (PRD_000369) Chemie (0Z6) | |||
| 6 | I, M, O, S (H, L, I, M) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | J, P (H, I) | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 8 | K, L (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 2 | Chemie (FUC) | |||
| 9 | Q (M) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 10 | R (M) | beta-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUL) | |||
| 11 | T, U (H, I) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 82591.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2115.0 | |
| All* | Total formula weight | 85049.1 |
