1CXZ
CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1
Summary for 1CXZ
Entry DOI | 10.2210/pdb1cxz/pdb |
Related | 1A2B |
Descriptor | PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), PROTEIN (PKN), MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | protein-protein complex, antiparallel coiled-coil, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 Cytoplasm : Q16512 |
Total number of polymer chains | 2 |
Total formula weight | 30971.42 |
Authors | Maesaki, R.,Ihara, K.,Shimizu, T.,Kuroda, S.,Kaibuchi, K.,Hakoshima, T. (deposition date: 1999-08-31, release date: 1999-10-08, Last modification date: 2024-05-22) |
Primary citation | Maesaki, R.,Ihara, K.,Shimizu, T.,Kuroda, S.,Kaibuchi, K.,Hakoshima, T. The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Mol.Cell, 4:793-803, 1999 Cited by PubMed: 10619026DOI: 10.1016/S1097-2765(00)80389-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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