1BQQ
CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX
Summary for 1BQQ
Entry DOI | 10.2210/pdb1bqq/pdb |
Descriptor | MEMBRANE-TYPE MATRIX METALLOPROTEINASE, METALLOPROTEINASE INHIBITOR 2, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | matrix metalloproteinase, tissue inhibitor of metalloproteinases, proteinase complex, pro-gelatinase a activator, complex (metalloproteinase-receptor), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein (Potential): P50281 Secreted: P16368 |
Total number of polymer chains | 2 |
Total formula weight | 40535.47 |
Authors | Fernandez-Catalan, C.,Bode, W.,Huber, R.,Turk, D.,Calvete, J.J.,Lichte, A.,Tschesche, H.,Maskos, K. (deposition date: 1998-08-18, release date: 1999-08-18, Last modification date: 2011-07-13) |
Primary citation | Fernandez-Catalan, C.,Bode, W.,Huber, R.,Turk, D.,Calvete, J.J.,Lichte, A.,Tschesche, H.,Maskos, K. Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. EMBO J., 17:5238-5248, 1998 Cited by PubMed: 9724659DOI: 10.1093/emboj/17.17.5238 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
Download full validation report