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1BQQ

CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(M)
MEMBRANE-TYPE MATRIX METALLOPROTEINASEpolymer17419795.81UniProt (P50281)
Pfam (PF00413)
Homo sapiens (human)CDMT1-MMP; MATRIX METALLOPROTEINASE-14; MMP-14; MT-MMP 1; MTMMP1
2B
(T)
METALLOPROTEINASE INHIBITOR 2polymer18420528.71UniProt (P16368)
Pfam (PF00965)
Bos taurus (cattle)TIMP-2; TISSUE INHIBITOR OF METALLOPROTEINASES-2; COLLAGENASE INHIBITOR
3C, F
(M)
CALCIUM IONnon-polymer40.12Chemie (CA)
4D, E
(M)
ZINC IONnon-polymer65.42Chemie (ZN)
5G, H
(M, T)
waterwater18.0311Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40324.5
Non-Polymers*Number of molecules4
Total formula weight211.0
All*Total formula weight40535.5
*Water molecules are not included.

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PDB entries from 2025-07-02

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