1A7Z

CRYSTAL STRUCTURE OF ACTINOMYCIN Z3

1A7Z の概要

• エントリーDOI: 10.2210/pdb1a7z/pdb
• 関連するPDBエントリー: 173D 1A7Y 1DSC 1DSD 1FJA 1I3W 1L1V 1MNV 1OVF 1QFI 1UNJ 1UNM 209D 2D55 316D
• 関連するBIRD辞書のPRD_ID: PRD_000009
• 分子名称: ACTINOMYCIN Z3, BENZENE (3 entities in total)
• 機能のキーワード: actinomycin d, actinomycin, anticancer, antitumor, chromophore, depsipeptide, antibiotic
• 由来する生物種: STREPTOMYCES FRADIAE
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4273.99

構造登録者

Schafer, M. (登録日: 1998-03-19, 公開日: 1999-03-23, 最終更新日: 2024-07-10)

主引用文献

Schafer, M.,Sheldrick, G.M.,Bahner, I.,Lackner, H.
Crystal Structures of Actinomycin D and Actinomycin Z3.
Angew.Chem.Int.Ed.Engl., 37:2381-2384, 1998

PubMed Abstract: Untwinned single crystals of the actinomycins D and Z that diffracted to atomic resolution could be obtained for the first time. Low-temperature data collection and a new ab initio method for solving the structures led to precise crystal structures which showed, for example, that the unit cell of actinomycin D contains three molecules, two of which are present in the form of a hydrogen-bridged dimer related by a pseudo-twofold axis (see picture).

PubMed: 29710967
DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2381::AID-ANIE2381>3.0.CO;2-L

実験手法

X-RAY DIFFRACTION (0.95 Å)