1A4R

G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM

1A4R の概要

• エントリーDOI: 10.2210/pdb1a4r/pdb
• 分子名称: G25K GTP-BINDING PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: hydrolase, gtpase, signal transduction
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43561.04

構造登録者

Rudolph, M.G.,Vetter, I.R.,Wittinghofer, A. (登録日: 1998-02-02, 公開日: 1999-03-02, 最終更新日: 2023-08-02)

• 主引用文献: Rudolph, M.G.,Wittinghofer, A.,Vetter, I.R.; Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.; Protein Sci., 8:778-787, 1999; PubMed: 10211824

実験手法

X-RAY DIFFRACTION (2.5 Å)