1A4I
HUMAN TETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE
Summary for 1A4I
Entry DOI | 10.2210/pdb1a4i/pdb |
Descriptor | METHYLENETETRAHYDROFOLATE DEHYDROGENASE / METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | thf, bifunctional, dehydrogenase, cyclohydrolase, folate, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P11586 |
Total number of polymer chains | 2 |
Total formula weight | 66791.93 |
Authors | Allaire, M.,Li, Y.,Mackenzie, R.E.,Cygler, M. (deposition date: 1998-01-30, release date: 1999-02-09, Last modification date: 2024-02-07) |
Primary citation | Allaire, M.,Li, Y.,MacKenzie, R.E.,Cygler, M. The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution. Structure, 6:173-182, 1998 Cited by PubMed: 9519408DOI: 10.1016/S0969-2126(98)00019-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
Download full validation report