1YC0
short form HGFA with first Kunitz domain from HAI-1
Summary for 1YC0
Entry DOI | 10.2210/pdb1yc0/pdb |
Related | 1YBW |
Descriptor | Hepatocyte growth factor activator, Kunitz-type protease inhibitor 1, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase/inhibitor, hydrolase-inhibitor complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q04756 O43278 |
Total number of polymer chains | 2 |
Total formula weight | 39921.19 |
Authors | Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C. (deposition date: 2004-12-21, release date: 2005-02-15, Last modification date: 2023-08-23) |
Primary citation | Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C. Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B. J.Mol.Biol., 346:1335-1349, 2005 Cited by PubMed: 15713485DOI: 10.1016/j.jmb.2004.12.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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