1YC0
short form HGFA with first Kunitz domain from HAI-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hepatocyte growth factor activator | polymer | 283 | 30885.2 | 1 | UniProt (Q04756) Pfam (PF00089) | Homo sapiens (human) | HGF activator, HGFA |
| 2 | B (I) | Kunitz-type protease inhibitor 1 | polymer | 75 | 8941.1 | 1 | UniProt (O43278) Pfam (PF00014) | Homo sapiens (human) | Hepatocyte growth factor activator inhibitor type 1, HAI-1, KUNITZ DOMAIN FROM HAI-1 |
| 3 | C (I) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D, E (A, I) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
I: 245 - 303 (UniProt: O43278)
| PDB | External Database | Details |
|---|---|---|
| Met 229 | - | cloning artifact |
| Lys 230 | - | cloning artifact |
| His 231 | - | cloning artifact |
| Gln 232 | - | cloning artifact |
| His 233 | - | cloning artifact |
| Gln 234 | - | cloning artifact |
| His 235 | - | cloning artifact |
| Gln 236 | - | cloning artifact |
| His 237 | - | cloning artifact |
| Gln 238 | - | cloning artifact |
| His 239 | - | cloning artifact |
| Gln 240 | - | cloning artifact |
| His 241 | - | cloning artifact |
| Gln 242 | - | cloning artifact |
| Met 243 | - | cloning artifact |
| His 244 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39826.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 39921.2 |
