1YBW

Protease domain of HGFA with no inhibitor

Summary for 1YBW

• Entry DOI: 10.2210/pdb1ybw/pdb
• Descriptor: Hepatocyte growth factor activator precursor, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 62212.72

Authors

Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C. (deposition date: 2004-12-21, release date: 2005-02-15, Last modification date: 2023-08-23)

• Primary citation: Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C.; Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.; J.Mol.Biol., 346:1335-1349, 2005; PubMed: 15713485; DOI: 10.1016/j.jmb.2004.12.048

Experimental method

X-RAY DIFFRACTION (2.7 Å)