1YBW
Protease domain of HGFA with no inhibitor
Summary for 1YBW
Entry DOI | 10.2210/pdb1ybw/pdb |
Descriptor | Hepatocyte growth factor activator precursor, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 62212.72 |
Authors | Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C. (deposition date: 2004-12-21, release date: 2005-02-15, Last modification date: 2023-08-23) |
Primary citation | Shia, S.,Stamos, J.,Kirchhofer, D.,Fan, B.,Wu, J.,Corpuz, R.T.,Santell, L.,Lazarus, R.A.,Eigenbrot, C. Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B. J.Mol.Biol., 346:1335-1349, 2005 Cited by PubMed: 15713485DOI: 10.1016/j.jmb.2004.12.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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