1XHY

X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution

Summary for 1XHY

• Entry DOI: 10.2210/pdb1xhy/pdb
• Related: 1fw0
• Descriptor: Glutamate receptor, SULFATE ION, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ... (4 entities in total)
• Functional Keywords: ionotropic glutamate receptor glur2, mutant, ligand-binding core, kainate complex, membrane protein
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cell membrane; Multi-pass membrane protein: P19491
• Total number of polymer chains: 1
• Total formula weight: 29899.23

Authors

Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. (deposition date: 2004-09-21, release date: 2005-03-22, Last modification date: 2023-08-23)

• Primary citation: Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Fattorusso, C.,Gajhede, M.,Schousboe, A.,Kastrup, J.S.; Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.; Mol.Pharmacol., 67:703-713, 2005; PubMed: 15591246; DOI: 10.1124/mol.104.002931

Experimental method

X-RAY DIFFRACTION (1.85 Å)