1XHY
X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor | polymer | 263 | 29205.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | B, C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G (A) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 1 | Chemie (KAI) PubChem (3816) PubChem (10255) PubChem (73345) PubChem (23616889) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6453379) PubChem (6604705) PubChem (10036135) PubChem (11095940) PubChem (6603893) PubChem (101994997) PubChem (135037246) | |||
| 4 | H (A) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 0 - 114 (UniProt: P19491)
A: 117 - 260 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ala -1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 115 | - | linker |
| Thr 116 | - | linker |
| Phe 187 | Tyr 723 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29205.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 693.5 | |
| All* | Total formula weight | 29899.2 |
