1W88
The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2
Summary for 1W88
Entry DOI | 10.2210/pdb1w88/pdb |
Related | 1B5S 1EBD 1LAB 1LAC 1W3D 1W4E 1W4F 1W4G 1W4H 1W85 2PDD 2PDE |
Descriptor | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT, PYRUVATE DEHYDROGENASE E1 COMPONENT, BETA SUBUNIT, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, ... (6 entities in total) |
Functional Keywords | pyruvate dehydrogenase, dihydrolipoyl, acetyl transferase, multienzyme complex, oxidoreductase, transferase, catalysis, slinky |
Biological source | GEOBACILLUS STEAROTHERMOPHILUS More |
Total number of polymer chains | 10 |
Total formula weight | 319320.48 |
Authors | Frank, R.A.W.,Pratap, J.V.,Pei, X.Y.,Perham, R.N.,Luisi, B.F. (deposition date: 2004-09-16, release date: 2004-11-02, Last modification date: 2023-12-13) |
Primary citation | Frank, R.A.W.,Titman, C.M.,Pratap, J.V.,Luisi, B.F.,Perham, R.N. A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes Science, 306:872-, 2004 Cited by PubMed: 15514159DOI: 10.1126/SCIENCE.1101030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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