1W78
E.coli FolC in complex with DHPP and ADP
Summary for 1W78
Entry DOI | 10.2210/pdb1w78/pdb |
Related | 1W7K |
Descriptor | FOLC BIFUNCTIONAL PROTEIN, PHOSPHORYLATED DIHYDROPTEROATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | folc, dhfs, dihydrofolate synthase, synthase, atp-binding, folate biosynthesis, ligase, multifunctional enzyme |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 1 |
Total formula weight | 46463.68 |
Authors | Mathieu, M.,Debousker, G.,Vincent, S.,Viviani, F.,Bamas-Jacques, N.,Mikol, V. (deposition date: 2004-08-31, release date: 2005-02-09, Last modification date: 2023-12-13) |
Primary citation | Mathieu, M.,Debousker, G.,Vincent, S.,Viviani, F.,Bamas-Jacques, N.,Mikol, V. Escherichia Coli Folc Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-Microbial Therapy J.Biol.Chem., 280:18916-, 2005 Cited by PubMed: 15705579DOI: 10.1074/JBC.M413799200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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