1UYM
Human Hsp90-beta with PU3 (9-Butyl-8(3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine)
Summary for 1UYM
Entry DOI | 10.2210/pdb1uym/pdb |
Related | 1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYD 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1YER 1YES 1YET |
Descriptor | HEAT SHOCK PROTEIN HSP 90-BETA, 9-BUTYL-8-(3,4,5-TRIMETHOXYBENZYL)-9H-PURIN-6-AMINE (3 entities in total) |
Functional Keywords | hsp90, atpase, pu3, chaperone, atp-binding, heat shock |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : P08238 |
Total number of polymer chains | 1 |
Total formula weight | 25043.27 |
Authors | Wright, L.,Barril, X.,Dymock, B.,Sheridan, L.,Surgenor, A.,Beswick, M.,Drysdale, M.,Collier, A.,Massey, A.,Davies, N.,Fink, A.,Fromont, C.,Aherne, W.,Boxall, K.,Sharp, S.,Workman, P.,Hubbard, R.E. (deposition date: 2004-03-02, release date: 2004-08-17, Last modification date: 2023-12-13) |
Primary citation | Wright, L.,Barril, X.,Dymock, B.,Sheridan, L.,Surgenor, A.,Beswick, M.,Drysdale, M.,Collier, A.,Massey, A.,Davies, N.,Fink, A.,Fromont, C.,Aherne, W.,Boxall, K.,Sharp, S.,Workman, P.,Hubbard, R.E. Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms Chem.Biol., 11:775-, 2004 Cited by PubMed: 15217611DOI: 10.1016/J.CHEMBIOL.2004.03.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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