1UYD

Human Hsp90-alpha with 9-Butyl-8-(2-chloro-3,4,5-trimethoxy-benzyl)-9H-purin-6-ylamine

Summary for 1UYD
Related1BYQ 1OSF 1UY6 1UY7 1UY8 1UY9 1UYC 1UYE 1UYF 1UYG 1UYH 1UYI 1UYK 1UYL 1UYM 1YER 1YES 1YET
DescriptorHEAT SHOCK PROTEIN HSP 90-ALPHA, 9-BUTYL-8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-9H-PURIN-6-YLAMINE (3 entities in total)
Functional Keywordshsp90, atpase, pu8, chaperone, atp-binding, heat shock
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm : P07900
Total number of polymer chains1
Total formula weight27007.65
Authors
Primary citationAherne, W.,Barril, X.,Beswick, M.,Boxall, K.,Collier, A.,Davies, N.,Drysdale, M.,Dymock, B.,Fink, A.,Fromont, C.,Hubbard, R.E.,Massey, A.,Sharp, S.,Sheridan, L.,Surgenor, A.,Workman, P.,Wright, L.
Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms
Chem.Biol., 11:775-, 2004
PubMed: 15217611
DOI: 110.1016/J.CHEMBIOL.2004.03.033
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
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PDB entries from 2021-06-16