1TP0
Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.
Summary for 1TP0
| Entry DOI | 10.2210/pdb1tp0/pdb |
| Related | 1S0L 1T4Q 1TOO 1TWE 1TWM |
| Descriptor | Interleukin-1 beta (2 entities in total) |
| Functional Keywords | hydrophobic cavity, hydrophobicity, immune system |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytosol : P01584 |
| Total number of polymer chains | 1 |
| Total formula weight | 17512.94 |
| Authors | Adamek, D.H.,Guerrero, L.,Caspar, D.L. (deposition date: 2004-06-15, release date: 2005-02-08, Last modification date: 2024-02-14) |
| Primary citation | Adamek, D.H.,Guerrero, L.,Blaber, M.,Caspar, D.L. Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346:307-318, 2005 Cited by PubMed: 15663946DOI: 10.1016/j.jmb.2004.11.046 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report
