1TWM

Interleukin-1 Beta Mutant F146Y

Summary for 1TWM

Entry DOI	10.2210/pdb1twm/pdb
Related	1T4Q 1TOO 1TP0 1TWE 1s0l
Descriptor	Interleukin-1 beta (2 entities in total)
Functional Keywords	hydrophobic cavity, water, solvation, hydrophobicity, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted: P01584
Total number of polymer chains	1
Total formula weight	17411.83
Authors	Adamek, D.H.,Capsar, D.L. (deposition date: 2004-07-01, release date: 2004-12-07, Last modification date: 2024-02-14)
Primary citation	Adamek, D.H.,Guerrero, L.,Blaber, M.,Caspar, D.L. Structural and energetic consequences of mutations in a solvated hydrophobic cavity. J.Mol.Biol., 346:307-318, 2005 Cited by PubMed: 15663946 DOI: 10.1016/j.jmb.2004.11.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation