1TP0
Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-1 beta | polymer | 153 | 17512.9 | 1 | UniProt (P01584) Pfam (PF00340) | Homo sapiens (human) | IL-1 beta, Catabolin |
| 2 | B (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 153 (UniProt: P01584)
| PDB | External Database | Details |
|---|---|---|
| Trp 42 | Phe 158 | engineered mutation |
| Trp 101 | Phe 217 | engineered mutation |
| Trp 146 | Phe 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17512.9 | |
| All* | Total formula weight | 17512.9 |
