1RKW
CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO PENTAMADINE
Summary for 1RKW
Entry DOI | 10.2210/pdb1rkw/pdb |
Related | 1JT6 1JTX 1JTY 1JUM 1JUP 1JUS |
Descriptor | Transcriptional regulator qacR, SULFATE ION, 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, ... (4 entities in total) |
Functional Keywords | multidrug recognition, pent, qacr, multidrug binding protein, transcription |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 94385.90 |
Authors | Murray, D.S.,Schumacher, M.A.,Brennan, R.G. (deposition date: 2003-11-23, release date: 2004-06-01, Last modification date: 2023-08-23) |
Primary citation | Murray, D.S.,Schumacher, M.A.,Brennan, R.G. Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. J.Biol.Chem., 279:14365-14371, 2004 Cited by PubMed: 14726520DOI: 10.1074/jbc.M313870200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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