1P4L

Crystal structure of NK receptor Ly49C mutant with its MHC class I ligand H-2Kb

Summary for 1P4L

Entry DOI	10.2210/pdb1p4l/pdb
Related	1P1Z 1QO3 1VAC
Descriptor	MHC CLASS I H-2KB HEAVY CHAIN, Beta-2-microglobulin, Ovalbumin peptide, ... (4 entities in total)
Functional Keywords	natural killer receptor, mhc class i, c-type lectin-like domain, immune system
Biological source	Mus musculus (house mouse) More
Cellular location	Membrane; Single-pass type I membrane protein: P01901 Secreted: P01887 P01012 Membrane; Single-pass type II membrane protein: Q64329
Total number of polymer chains	4
Total formula weight	58828.92
Authors	Dam, J.,Guan, R.,Natarajan, K.,Dimasi, N.,Mariuzza, R.A. (deposition date: 2003-04-23, release date: 2003-11-11, Last modification date: 2023-08-16)
Primary citation	Dam, J.,Guan, R.,Natarajan, K.,Dimasi, N.,Chlewicki, L.K.,Kranz, D.M.,Schuck, P.,Margulies, D.H.,Mariuzza, R.A. Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nat.Immunol., 4:1213-1222, 2003 Cited by PubMed: 14595439 DOI: 10.1038/ni1006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation