1NZV
Crystal Structure of Src SH2 domain bound to doubly phosphorylated peptide PQpYIpYVPA
Summary for 1NZV
Entry DOI | 10.2210/pdb1nzv/pdb |
Related | 1ISO 1KC2 1NZL 1SPS |
Descriptor | Tyrosine-protein kinase transforming protein SRC, Doubly phosphorylated peptide PQpYIpYVPA, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | sh2 domain, phosphotyrosine, transferase |
Biological source | Rous sarcoma virus (strain Schmidt-Ruppin) |
Total number of polymer chains | 3 |
Total formula weight | 25059.88 |
Authors | Lubman, O.Y.,Waksman, G. (deposition date: 2003-02-19, release date: 2003-04-22, Last modification date: 2023-11-15) |
Primary citation | Lubman, O.Y.,Waksman, G. Structural and Thermodynamic Basis for the Interaction of the Src SH2 domain with the Activated form of the PDGF beta-receptor J.Mol.Biol., 328:655-668, 2003 Cited by PubMed: 12706723DOI: 10.1016/S0022-2836(03)00344-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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