1KC2
structure of the triple (Lys(beta)D3Ala, Asp(beta)C8Ala, AspCD2Ala) mutant of the Src SH2 domain bound to the PQpYEEIPI peptide
Summary for 1KC2
Entry DOI | 10.2210/pdb1kc2/pdb |
Descriptor | Src Tyrosine kinase, PQpYEEIPI peptide, COBALT (II) ION, ... (4 entities in total) |
Functional Keywords | sh2 domain, phosphotyrosine, transferase |
Biological source | Rous sarcoma virus More |
Total number of polymer chains | 2 |
Total formula weight | 12823.23 |
Authors | Lubman, O.Y.,Waksman, G. (deposition date: 2001-11-07, release date: 2002-04-17, Last modification date: 2021-11-10) |
Primary citation | Lubman, O.Y.,Waksman, G. Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface. J.Mol.Biol., 316:291-304, 2002 Cited by PubMed: 11851339DOI: 10.1006/jmbi.2001.5362 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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