2JMN
NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures
Replaces: 1LNPReplaces: 1VKSSummary for 2JMN
Entry DOI | 10.2210/pdb2jmn/pdb |
Related | 2H67 |
Descriptor | Insulin A chain, Insulin B chain (2 entities in total) |
Functional Keywords | hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5794.59 |
Authors | Hua, Q.X.,Hu, S.Q.,Frank, B.H.,Jia, W.H.,Chu, Y.C.,Wang, S.H.,Burke, G.T.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2006-11-21, release date: 2006-12-05, Last modification date: 2023-12-20) |
Primary citation | Hua, Q.X.,Hu, S.Q.,Frank, B.H.,Jia, W.,Chu, Y.C.,Wang, S.H.,Burke, G.T.,Katsoyannis, P.G.,Weiss, M.A. Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264:390-403, 1996 Cited by PubMed: 8951384DOI: 10.1006/jmbi.1996.0648 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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